| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2245aefaea2a24047376999b2602c8b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C8-0012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-3804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31678
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4202
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-30767 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C8-0013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61C8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30 |
| filingDate |
2003-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_798c6ea77e9c74ac91a149270c1285c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2348040fcd8463dc57b304d4d3526029
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae912a8c93c1085ab3046eb67dbea8ad |
| publicationDate |
2005-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1539261-A1 |
| titleOfInvention |
Metal implant coated under reduced oxygen concentration with osteoinductive protein |
| abstract |
The present invention relates to a method for producing a device comprising the steps of (a) providing a solution comprising dissolved osteoinductive protein, (b) contacting the solution of the preceding step with a carrier containing a surface of metal or a metal alloy, (c) allowing coating of the surface of said carrier with said dissolved protein and (d) drying of the coated carrier obtained in step (c) wherein steps (b) to (d) are carried out under a reduced concentration of oxygen. The invention also encompasses a device obtainable by the method of the present invention. Moreover, the present invention relates to a pharmaceutical composition comprising the said device and to the use of the device for the preparation of a pharmaceutical composition to be used for an accelerated osseointegration and new bone formation. Finally, the present invention relates to a kit comprising the device of the present invention. |
| priorityDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |