| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-204
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-208
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2003-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41e1fc26c73e9e091b1fb915e2d62aaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbfd814cb6772229e7224fbea9a19f49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fad8b7dfa96edcfbc2c3a85feb83cb60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53f13294acdece5168d45921f1aaf105 |
| publicationDate |
2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1536007-A1 |
| titleOfInvention |
Artificial mammalian chromosome |
| abstract |
It is intended to provide an artificial mammalian chromosome which is stably held in mammalian cells and allows efficient expression of a target gene carried thereby. Namely, a first cyclic vector containing a mammalian centromere sequence and a selection marker gene and a second cyclic vector containing a functional sequence are transferred into mammalian host cells. Then transformed cells are selected by using the above-described selection marker gene and cells holding an artificial mammalian chromosome are selected from among the transformed cells thus selected. Thus, it is possible to construct an artificial mammalian chromosome which has a mammalian replication origin, the mammalian centromere sequence and the functional sequence, is in a cyclic form, can be replicated in mammalian cells, extrachromosomally held in the host cells and transferred to daughter cells in cell division. <IMAGE> |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2445068-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2445068-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3954765-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012156721-A1 |
| priorityDate |
2002-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |