| abstract |
The present invention provides a compound representednby the formula (I):n n[wherein R is an optionally substituted hydrocarbon group ornan optionally substituted heterocyclic group, p is 0, 1 or 2,nand when p is 2, each R may be the same or different, R 1 isna hydrogen atom or an optionally substituted hydrocarbonngroup, R 2 is an optionally substituted aromatic group, Ring Anis an optionally substituted monocyclic aromatic ring ornoptionally substituted bicyclic aromatic fused ring, X 1 isnan oxygen atom or a sulfur atom, X 2 is a bond, an oxygennatom or -S(O) n - (wherein n is 0, 1 or 2), Y is a bond, annoxygen atom, -S(O) m -, -C(=O)-N(R 3 )- or -N(R 3 )-C(=O)- (R 3 is anhydrogen atom, an optionally substituted hydrocarbon groupnor an optionally substituted heterocyclic group, and m is 0,n1 or 2), M 1 , M 2 and M 3 may be the same or different and areneach independently a bond or an optionally substitutedndivalent aliphatic hydrocarbon group, and M 4 is annoptionally substituted divalent aliphatic hydrocarbon group]nor a salt thereof, which is useful as a prophylactic and/orntherapeutic agent for lipid metabolism abnormality, narteriosclerotic disease and sequelae thereof, diabetesnmellitus and the like. |