Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f841cb4135741a659c198bbbd057750b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-26003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04 |
filingDate |
2003-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a42eb79a80869196ae258f1d4bb61c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3384d79d6ab25942c5908a4de0b8cba8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3006430045c98dd2d2e2c159f98ac04b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32a91551481ca3ca7c28053f9979d299 |
publicationDate |
2005-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1532271-A2 |
titleOfInvention |
Methods and compositions relating to polypeptides with rnase iii domains that mediate rna interference |
abstract |
The present invention concerns methods and compositions involving RNase III and polypeptides containing RNase III domains to generate RNA capable of triggering RNA-mediated interference (RNAi) in a cell. In some embodiments, the RNase III is from a prokaryote. RNase III activity will cleave a double-stranded RNA molecule into short RNA molecules that may trigger or mediate RNAi (siRNA). Compositions of the invention include kits that include an RNase III domain-containing polypeptide. The present invention further concerns methods using polypeptides with RNase III activity for generating RNA molecules that effect RNAi, including the generation of a number of RNA molecules to the same target. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626398-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106793-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196640-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9796978-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9777275-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10036025-B2 |
priorityDate |
2002-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |