http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1525325-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_979005c40711970d0cc75b8f1fe9fa19 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-143 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 |
| filingDate | 2003-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6086a3df66f1986192742ac0d7b799a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19033f165b025bc7df2b0fe9e618cf4f |
| publicationDate | 2012-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1525325-B1 |
| titleOfInvention | Novel method for analyzing nucleic acid and use thereof for evaluating the degree of mrna editing of the serotonin 5-ht sb 2c /sb receptor |
| abstract | The invention concerns a method for analyzing nucleic acids using a small-size probe array comprising deoxyinosines (dI) instead of deoxyguanosines (dG). The invention also concerns such probe arrays and their use in methods for detecting and/or quantifying target oligonucleotides present in DNA (deoxyribonucleic acid) or RNA (ribonucleic acid) molecules in a sample, in particular mRNA editing rate of the serotonin 5-HT2C receptor (5-HT2C-R). The invention further concerns a biochip or a reactor in liquid medium comprising such probe arrays as well as their uses, in particular for detecting and/or identifying genetic polymorphisms or for determining an mRNA editing rate, whether it is that of a 5-HT2C-R mRNA or any other RNA capable of being edited. The invention also concerns a method based on the isolation of a single strand conformation polymorphism (SSCP) enabling under specific analysis conditions the editing profile and/or rate of an mRNA capable of being edited to be obtained, as well as a method for diagnosing diseases or susceptibility to diseases associated with the degree of edition of an mRNA. Finally, the invention concerns a method for selecting compounds capable of modulating mRNA editing rate, in particular that of 5-HT2C-R, as well as the use of such compounds for preparing a pharmaceutical composition for treating organic fluid. |
| priorityDate | 2002-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.