http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1518495-A1

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filingDate 2004-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebfbfe80d7d1a06b6769132e776a7e7b
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publicationDate 2005-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1518495-A1
titleOfInvention Method and device for continuous monitoring of analyte concentration
abstract Method for continuously monitoring the concentration of an analyte, in particular glucose, by determining its time course in the living body of a human or animal, in which measured values of a measured variable correlated with the desired concentration are measured as the measured signal ( z t ) and the time course of the concentration is determined as a useful signal ( y t ) from the measured signal, wherein the determination of the useful signal ( y t ) from the measured signal ( z t ) includes a filter algorithm in the time domain, wherein the filter algorithm includes an operation in which the influence of a current measured value on the useful signal is weighted by means of a weighting factor (V). The filter algorithm is preferably a Kalman filter algorithm. During the ongoing monitoring, a signal fluctuation parameter (σ t ) is determined on the basis of signal fluctuations detected in close temporal relation to the measurement of the current measured value. The weighting factor is dynamically adapted as a function of the signal fluctuation parameter determined for the time of the current measurement.
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