abstract |
The present invention relates to methyl transfer enzymes involved in alkaloid biosynthesis innopium poppy. More particularly, the invention relates to proteins having (R,S)-reticuline 7-O-methyltransferasenactivity, to proteins having ( R,S )-norcoclaurine 6- O -methyltransferasenactivity and to derivatives and analogues of these proteins. The invention also relates tonnucleic acid molecules encoding the proteins, and their derivatives and analogues, and tontheir use in the production of methylated catechols and tetrahydrobenzylisoquinolines. |