| abstract |
An electron transport system complex II inhibitorncomprising 2-pyridinol derivative represented by the generalnformula [I]n nwherein R is alkyl or alkenyl optionally having substituentncontaining halogen, or its tautomer 2-pyridone derivativenrepresented by the general formula [II]n nwherein R is alkyl or alkenyl optionally having substituentncontaining halogen, or salt thereof as an active ingredient.nThe compound inhibits the complex II strongly with nM ordernactivity. Consequently, 2-pyridinol derivative or its tautomer,n2-pyridone derivative, are useful as the complex II inhibitor. |