abstract |
Disclosing a promoter of the protease MDTS9, which isninduced by TGF-β, which is involved in the metabolism ofnextracellular matrix, and in which the expression of thengene thereof is elevated in renal failure model animals,nwhich promoter is useful as a tool for screening an agentnfor treating and/or preventing chronic renal failure, asnwell as a method for screening an agent for treating and/ornpreventing chronic renal failure by selecting an inhibitornof the promoter. |