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filingDate 2003-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfae87571bff8f5e8817dd07bd9b8e7a
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publicationDate 2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1507519-A1
titleOfInvention Medicament with delayed release of the active substance, containing 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol
abstract The invention relates to a pharmaceutical formulation with delayed release of the agent, containing 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol or one of the pharmaceutically acceptable salts thereof in a matrix. Said matrix contains 1 to 80 percent by weight of one or several hydrophilic or hydrophobic polymer/s as pharmaceutically acceptable matrix-forming substance/s and has the following dissolution rate: 3-35 percent by weight (relative to 100 percent by weight of active substance) of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 0.5 hours; 5-50 percent by weight of % 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 1 hour; 10-75 percent by weight of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 2 hours; 15-82 percent by weight of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 3 hours; 30-97 percent by weight of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 6 hours; more than 50 percent by weight of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 12 hours; more than 70 percent by weight of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 18 hours; more than 80 percent by weight of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol are released after 24 hours.
priorityDate 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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