| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate |
2003-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0e4bedc827b028bf472849a88feb219
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b24e45a49e92f9088ae93b3fe30b6873
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18739a859b38baa5b7b13d9e07340f9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f46c9411fb4d11649c4f7e949f99f32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_089db8d18cedf17c0ea818717062dbab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed1f0f8f25d4f33ca406433c1e95d033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81d234ea289bc5e547183f88a8bc93bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd1c03913f1df53d4271641d4f578dda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1a4ef1f9f7b0ea686f6b994122d32ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5119aa043fa49f41a855bca123fcf6c |
| publicationDate |
2005-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1506004-A2 |
| titleOfInvention |
Means for use in treating diseases correlated with or caused by non-physiological levels of microtubule-associated pp2ac |
| abstract |
The present invention relates to a method of preventing or treating a disease correlated with or caused by non-physiologically increased intracellular levels of the catalytic subunit of microtubule-associated protein phosphatase 2A (PP2Ac) comprising administering to a subject affected by said disease or in danger of developing said disease a pharmaceutically effective amount of a protein selected from the group of MID1 or MID2 or a nucleic acid encoding said protein. The invention further relates to a method of preventing or treating a disease correlated with or caused by non-physiologically decreased intracellular levels of the catalytic subunit of microtubule-associated protein phosphatase 2A (PP2Ac) comprising administering to a subject affected by said disease or in danger of developing said disease a pharmaceutically effective amount of a peptidic fragment of MID1 or MID2 wherein said peptidic fragment comprises amino acids 108-165 (preferably 110-165) of MID1, amino acids 108-165 (preferably 110-165) of MID2 or with an effective amount of a fragment of PP2Ac wherein said fragment comprises the binding site to a4 or of a peptide fragment of a4 comprising amino acids 236-279 or with an effective amount of a nucleic acid molecule encoding said peptide fragment or with an effective amount of a molecule interfering with the interaction of MID1 with a4 or with an effective amount of a molecule interfering with the expression or activity of MID1 and/or a 4. |
| priorityDate |
2002-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |