abstract |
The invention relates to the application of oligonucleotide and polypeptide sequences of molecules belonging tonthe vascular permeability factor (VPF) family, their receptors and co-receptors and to their modifications in active immunotherapynagainst pathological entities whose course is associated with an increase in vasculature. Said procedures can be used, inter alia, innmonotherapy or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectiousndiseases, autoimmune diseases, diabetic and infant retinopathy, rejection of transplanted organs, macular degeneration, neovascularnglaucoma, hemangioma and angiofibroma. |