http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1499595-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fa8ab93121d379e71802274fc3d35e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2003-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f62887bcbd0a8ada64d62d3544e77f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be48700f9e5379064e6de06430b4f0a5 |
| publicationDate | 2005-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1499595-A1 |
| titleOfInvention | Amonafide salts |
| abstract | Disclosed is a salt of amonafide or amonafide analogs represented Structural Formula (I): R1 is -(CH<SUB>2</SUB>)<SUB>n</SUB>N<SUP>+</SUP>HR3R4 X<SUP>-</SUP> or R1 is -(CH<SUB>2</SUB>)<SUB>n</SUB>N<SUP>+</SUP>HR3R4 X<SUP>-</SUP> or -(CH<SUB>2</SUB>)<SUB>n</SUB>NR3R4 when R2 is -N<SUP>+</SUP>HR6R7. R2 is -OR5, halogen, -NR6R7, -N<SUP>+</SUP>HR6R7 X<SUP>-</SUP>' sulphonic acid, nitro, -NR5COOR5, -NR5COR5 or -OCOR5; R3 and R4 are independently H, C1-C4 alkyl group or, taken together with the nitrogen atom to which they are bonded, a non-aromatic nitrogen-containing heterocyclic group; each R5 is independently -H or a C1-C4 alkyl group; R6 and R7 are independently H, C1-C4 alkyl group or, taken together with the nitrogen atom to which they are bonded, a non-aromatic nitrogen-containing heterocyclic group; n is an integer from 0-3; and X<SUP>-</SUP> is the carboxylate anion of an organic carboxylic acid compound. Also disclosed are methods of preparing certain compounds represented by Structural Formula (I). |
| priorityDate | 2002-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 146.