| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f70c1c4ba071d62460b17f9f396a1aa8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate |
2003-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_281bf190378da7254be89b7d9fbb05d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58c11dd15adacd9cb0ee5dd72d9ab69f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6e0bcceeb63097314d3528fadcf0560
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d875c189fcc09fa268e00afa38e57958 |
| publicationDate |
2005-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1497323-A1 |
| titleOfInvention |
Multiple branch peptide constructions comprising from 2 to 16 branches of the peptide rqgys or from 8 to 16 branches of the peptide rqgy providing from the hiv gp41 glycoprotein |
| abstract |
Multiple branch peptide constructions formed from peptides derived from the envelope transmembrane glycoprotein gp41 of HIV, and including from 2 to 16 branches of the peptide RQGYS or from 8 to 16 branches of the peptide RQGY, show increased receptor affinity and prevent cell-to-cell fusion. They have a direct virostatic effect. These MBPCs are able to neutralize in vitro the different steps of virus envelope/cell membrane fusion, and infected cell membrane/uninfected cell membrane fusion of several strains of HIV-1 and HIV-2. These results open a potential use in treatment of HIV infection. |
| priorityDate |
2002-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |