| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e14d6eb6e2b529693a4fd5c5238b4e4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-6555 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2003-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0460a25be8653074977a261b68aa8e70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87fb6d5109112bbfe24b3bf759090bed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d02e5d661a517ad5ea34640cfed917
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1437860f446c394298684699bd0433d |
| publicationDate |
2005-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1494694-A2 |
| titleOfInvention |
Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging |
| abstract |
Novel photo-active labeled diagnostic and therapeutic peptides which are conformationally constrained backbone cyclized somatostatin analogs, having improved somatostatin receptor subtype affinity and selectivity are disclosed. The backbone cyclized peptide analogs disclosed possess unique and superior properties over other analogs, such as chemical and metabolic stability, selectivity, increased bioavailability and improved pharmacokinetics. Furthermore, the unique patterns of receptor subtype selectivity provide compounds having improved diagnostic and therapeutic utilities. Pharmaceutical compositions comprising the photo-active backbone cyclized somatostatin analogs, reagents for synthesizing same, and methods of using such compositions for diagnostic and therapeutic purposes including optical imaging and photodynamic therapy are also disclosed. |
| priorityDate |
2002-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |