http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1493434-A1

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filingDate 1999-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2005-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1493434-A1
titleOfInvention Extended release acetaminophen
abstract An extended release acetaminophen composition comprises particles containing acetaminophen coated on sugar/starch seeds. The particles are present as a blend of both an immediate release and a controlled release form. The composition, when contained within a gelatin capsule and assayed in a USP Apparatus I rotating basket at 50 rpm in 900 mL of phosphate buffer at pH 5.8 and a temperature of 37 °C, exhibits about 40 percent acetaminophen dissolution at one-half hour, about 55 percent acetaminophen dissolution at one hour, and substantially complete dissolution of acetaminophen at six hours. A process for treating a human patient with the extended release acetaminophen composition is also disclosed.
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