| abstract |
The present invention discloses compounds of the formulan any of its enantiomers or any mixture thereof, isotopes thereof or a pharmaceutically acceptable salt thereof; nwherein n n is 1,2 or 3; n m is 0,1 or 2; n R represents hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, or aralkyl; and nR 1 represents aminophenyl; nitrophenyl; hydroxyphenyl, alkoxyphenyl; na monocyclic 5 to 6 membered heterocyclic group which may be substituted one or more times nor R 1 represents a bicyclic heterocyclic group, composed of a 5 to 6 membered monocyclic heterocyclic group fused to a benzene ring, and which may be substituted one or more times. n The compounds of the invention are useful as nicotinic ACh receptor ligands. |