abstract |
It is intended to provide a liquid matrix for medicinalnuse in which medicine can be easily solubilized, dispersed ornsuspended and which can be easily swallowed because of beingnliquid, has favorable working properties in sterilization andnso on and a high stability, also exhibits an effect ofnmasking bitterness, and gels in vivo so as to control thenrelease speed of the medicine, and liquid oral preparationsnusing the same. Namely, a liquid matrix which is a liquidnassistant for facilitating swallowing medicine characterizednin comprising a water-soluble polymer gelling under acidicnconditions, and the breaking stress of the gel is about 3.00nĂ—10 3 N/m 2 or more. Liquid oral preparations have favorablenslow release properties even though being a liquid. |