| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f173732eb4ab7d0f2de7b3808763a640
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b727a28f5165b4c3409333871fcaa147
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4afb8b01aa8de7e0b24a86713b23a18 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-20 |
| filingDate |
2003-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c43dda598e1cd77a5e1aafbe8e7eed5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8065fd5750c76cbec7e7a459db7434f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7e17637024bfbdff0a50b631430c4c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef2a134a3a8bc10c675b683d4fb91d89 |
| publicationDate |
2004-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1484336-A1 |
| titleOfInvention |
Methods for synthesizing conformationally constrained peptides, peptidometics and the use thereof as synthetic vaccines |
| abstract |
The present invention relates to methods for synthesizingnconformationally constrained peptides and cyclicnpeptidomimetics obtainable by these methods which arenconformationally constrained due an internal cross-link. Thisncross-link is formed between the side chain of an amino acidnresidue or analog and a (2S,4S)-4-functionalized prolinenresidue. The invention further relates to the use of (2S,4S)-4-functionalizednproline residues as building units in thensynthesis of such peptidomimetics and to the use thereof asnantigens, alone or in combination with suitablenimmunopotentiating delivery systems, for examplenimmunopotentiating reconstituted influenza virosomes tonelicit an immune response in a mammal. Moreover, theninvention also relates to pharmaceutical compositionsncontaining the same. |
| priorityDate |
2003-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |