| abstract |
A JNK inhibitor containing a compound having annisoquinolinone skeleton or a salt thereof, such as a compoundnrepresented by the formulan nwherein ring A and ring B are each an optionally substitutednbenzene ring, X is -O-, -N=, -NR 3 - or -CHR 3 -, R 2 is an acylngroup, an optionally esterified or thioesterified carboxylngroup, an optionally substituted carbamoyl group or annoptionally substituted amino group and the like, a broken linenshows a single bond or a double bond, and R 1 is a hydrogen atom,nan optionally substituted hydrocarbon group, an optionallynsubstituted heterocyclic group and the like, and the like. |