| abstract |
Certain cells, including types of cancer cells such as B-cell lymphoma, T-cell lymphoma, T-cell leukemia, multiple myeloma, and Hodgkin's Disease, are capable of expressing cell surface antigen RNA and proteins. Targeting using cell surface antigen polypeptides, nucleic acids encoding for cell surface antigen polypeptides, antibodies specific for cell surface antigens, and small molecules and peptides that bind to or recognize said cell surface antigens, provides a method of killing or inhibiting that growth of cells that express the cell surface antigen protein. Methods of therapy and diagnosis of disorders associated with cell surface protein-expressing cells are described. |