abstract |
The invention discloses an aerosol pharmaceutical composition comprising a medicament in solution in a mixture of a hydrofluoroalkane propellant and one or more co-solvents wherein the aerosol liquid droplets delivered on actuation of the inhaler have a particle size comprised between 0,5 microm and 2.5 microm, with a mass median aerodynamic diameter of about 1-2 microm and wherein the fine particle fraction is at least 30%. |