| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f6cd0d9c1f8c74d6457c8f9440b0690 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 |
| filingDate |
1999-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c43857863a95c29efd792b10d62a4e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1961cf6edffc79426c0781b2fe808deb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84cf4c902dc8fdae43dd193e56fcee93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d8c52a916f14a8170ef507d185d9d44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c5ca26168568bea8c6fcc3dd7b42d7d |
| publicationDate |
2004-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1479382-A1 |
| titleOfInvention |
Oral pharmaceutical compositions containing taxanes and methods for treatment employing the same |
| abstract |
Pharmaceutical compositions for oral administration to mammalian subjects comprisena taxane or taxane derivative (e.g. paclitaxel or docetaxel) as active ingredient and a vehiclencomprising at least 30% by weight of a carrier for the taxane, said carrier having an HLBnvalue of at least about 10. The compositions may also comprise 0 - 70% of a viscosity-reducingnco-solubilizer. The compositions may be incorporated into conventional oralnpharmaceutical dosage forms, or can be in the form of a two-part medicament wherein thenfirst part includes the taxane in a solubilizing vehicle and the second part comprises a carriernfor the taxane to promote oral absorption. Methods of treatment of taxane-responsive diseasenconditions employing the novel compositions are also disclosed, whereby the compositionsncan be administered alone or in association with an oral bioavailability enhancing agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9308195-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2344674-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010015400-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9763880-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10842770-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8940786-B2 |
| priorityDate |
1999-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |