| abstract |
The invention provides compounds of Formula I: (1) wherein Azabicyclo is (2) W is a six-membered heterocyclic ring system having 1-2 nitrogen atoms or a 10-membered bicyclic-six-six-fused-ring system having up to two nitrogen atoms within either or both rings, provided that no nitrogen is at a bridge of ten bicyclic-six-six-fused-ring system, and further having 1-2 substituents independently selected from R3. These compounds may be in the form of pharamaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharamaceuticals to treat diseases or conditions in which α7 is known t be involved. |