| abstract |
(I) Pyrrolo[3,2-d] pyrimidine derivatives represented by the above general formula (I) or pharmaceutically acceptable salts thereof. Because of having a GSK-3 inhibitory effect, these compounds are expected as being useful as remedies or preventives for diseases in which GSK-3 participates such as diabetes, diabetic complications, Alzheimer’s disease, neurodegenerative disease, depression and mania, traumatic brain injury, hair loss, inflammatory diseases, cancer and immunodeficiency. |