| abstract |
A compound represented by the general formula (I):[wherein n is an integer of 1 to 3; R represents C3-8 alkyl, a group represented by R1(CH2)k- (k is an integer of 0 to 3; and R1 represents C3-7 saturated cycloalkyl or C6-8 fused-ring saturated alkyl, provided that R1 may be substituted by C1-4 alkyl), etc.; and Ar represents a bicyclic fused-ring group, e.g., naphthalen-1-yl] or a salt of the compound. The compound or salt has prostaglandin and leukotriene production inhibitory activity. It is useful for the prevention of and treatments for, e.g., various inflammatory diseases attributable to the lipid mediator. |