| abstract |
The invention provides use of a compound of formula (I): or a salt thereof, wherein:R1 is 125I, 124I, 123I, 75Br, 76Br, or 18F; R2 is C1-6 alkyl; and R3 is selected from hydrogen, C1-6 alkyl, -C(O) C1-.6 alkyl, -C(O)C1-6 haloalkyl, and -C(O)CH(R4)NH2 ; wherein R4 is selected from hydrogen, C1-6alkyl, C1-6hydroxyalkyl, and C1-6aminoalkyl; for the manufacture of a radiopharmaceutical for the in vivo diagnosis or imaging of an amyloid-associated disease, particularly Alzheimer's disease. |