Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14322 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2003-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a00b6af64d15812fb3236604f20f911b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f099443c795739360d91d1b14622df6 |
publicationDate |
2004-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1473306-A1 |
titleOfInvention |
Fusion polypeptide suitable as a cytotoxin |
abstract |
Described are fusion polypeptides comprising (a) a binding site for ancytoskeleton component derived from Minute virus of Mice (MVM)nnon-structural protein -1 (NS-1) and (b 1 ) casein kinasenII-alpha (CKIIα) as effector protein or the catalytic domainnthereof or (b 2 ) a binding site for said effector protein, andnnucleic acid sequences encoding said fusion polypeptides. Moreover,nvarious therapeutic uses of said fusion polypeptides are decribed, e.g.,nthe treatment of diseases associated with the presence of an aberrantncell population, preferably cancer or AIDS. |
priorityDate |
2003-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |