http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1470234-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8357c79568c61ef7fd3548ab06e0b728 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-08 |
| filingDate | 2002-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa145bb0ed2f7c4cd132ef5c1d841653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e589f18d9412bced0d1a0e5132e2f6 |
| publicationDate | 2004-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1470234-A1 |
| titleOfInvention | Enzymatic synthesis of n(alpha)-acyl-l-arginine esters |
| abstract | The invention relates to a process for preparing a Na-acyl-L-arginine ester, derived from fatty acids and esterified dibasic amino acids, according to the following formula (I), where:X- is Br-, Cl-, or HSO4- R1: is linear alkyl chain from an saturated fatty acid, or hydroxy-acid from 8 to 14 atoms of carbon bonded to the ∝- amino acid group through amidic bond. R2: is a linear or branched alkyl chain from 1 to 18 carbon atoms or aromatic. R3: is formula (II), where n can be from 0 to 4, from the appropriate organic acid and alcohol. The process is catalyzed by a hydrolase, more in particular a protease, the protease papain from ∫i⊃Carica papaya being highly suitable∫/i⊃. In order for the esterification reaction to run as wanted, the process is performed in a low-water-content organic medium. When the highly suitable papain from Carica papaya is used, a water activity of between 0,03 and 0,5 is selected. |
| priorityDate | 2002-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.