http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1465855-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6087ccfb4e25b2ad1c96725097ce0c5b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J3-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| filingDate | 2002-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_505220faf929b3e8c1edd68191c0af15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eb60fdaa84087e3b0e3b252e1add66b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dedea40d2be5e1df50357f7e63d3e847 |
| publicationDate | 2004-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1465855-A2 |
| titleOfInvention | Method for the production of 6-alpha-fluoro corticosteroids |
| abstract | A method for producing a 6a-fluorinated corticosteroid or derivative thereof by reacting a17-hydroxy-21-ester epoxide of Formula (II) with a stereoselective fluorinating agent to stereoselectively form a 21-ester-17-hydroxy 6a-fluorinated compound of Formula (VII) R1 can be OC(O)-Rd; R4 can be C(O)-Rd; R3 can be H or Rd. Each Rd may be the same or different and is independently selected from (C1-4)alkyl, aryl and heteroaryl. The dashed line can be a single or a double bond. R4 may be, for example, acetyl; R3 may be, for example, alpha or beta methyl; R1 may be, for example, acetate or propionate. The stereoselective fluorinating agent used in the reaction may be, for example, a fluoropyridinium or fluoroquinuclidium compound, for example, Selectfluor®. |
| priorityDate | 2001-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.