| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bf76e4f6afcc906b5ab076bb44dd2db |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4746 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2003-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45ec2403004e6410b5b2403f91d12229
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f51cb6029cd55c43574564f52bece475 |
| publicationDate |
2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1462521-A1 |
| titleOfInvention |
Human p53 splice variant displaying differential transcriptional activity |
| abstract |
Described is a nucleic acid molecule encoding a p53 variantncharacterized in that it is capable of transactivating thenp21- and 14-3-3σ -promoter but not the mdm2-, bax- and PIG3-promoter.nPreferably, in said p53 variant exon 7, exon 8 and/ornexon 9 are partially or entirely deleted. Finally, means forninhibiting the activity of this p53 variant are describednwhich are useful for the therapy of cancer. |
| priorityDate |
2003-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |