http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1462447-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 |
| filingDate | 2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcdefeccbb19703e609c591b5f35f7d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fab9bd5f2956a73ab96a12ae41662b6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c75f07838a8a23c74523afb6436a2ab3 |
| publicationDate | 2004-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1462447-A3 |
| titleOfInvention | Method for the preparation of pure citalopram |
| abstract | The present invention relates to a method for the preparation of purified citalopram of formulan nby removal of desmethyl citalopram having the formulan ncomprising optionally subjecting a crude citalopram product containing the desmethyl citalopramnimpurity to some initial purification and subsequently treating the crude product with an amide or annamide-like group forming agent selected from the agents of Formulas (a), (b) or (c):n nwhere X is halogen or a group O-CO-R', Hal is halogen, Y is O or S, W is O, N or S and R, R', R"nand R'" are each selected from the group consisting of hydrogen, alkyl, and optionally substitutednaryl or aralkyl; nthe reaction mixture is then subjected to an acid/base wash and/or crystallisation and recrystallisationnof citalopram in order to remove the amides formed from the crude citalopram mixture; and nthe resulting citalopram product is optionally further purified, worled up and isolated as the base orna pharmaceutically acceptable salt thereof. |
| priorityDate | 2000-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.