http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1457573-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d8d30805708f0d2affd52c695145421 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00612 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00637 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2003-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7ab5cd409b7444f0085ac5af568a0a8 |
| publicationDate | 2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1457573-A1 |
| titleOfInvention | Method and device for integrated nucleic acid integrity assessment and analysis |
| abstract | The present invention relates to methods for integrated ribonucleic acid integrity assessment andnanalysis comprising the steps of:n (a) providing a support having immobilized thereon a set of detector probes and a setnof at least two control probes, whereinn (i) a first of said at least two control probes is complementary to 23S or 28S rRNAnor a functionally equivalent rRNA, and (ii) a second of said at least two control probes is complementary to 16S or 18SnrRNA or a functionally equivalent rRNA; (b) contacting said support with analyte ribonucleic acids derived from a sample,nunder conditions allowing hybridisation of complementary analyte ribonucleic acidsnand immobilized probes to form analyte ribonucleic acid/probe complexes; whereinnsaid hybridisation generates a detectable signal; (c) detecting signals generated by said complexes; (d) determining the ratio of signals generated by the 285/control probe and 18SnrRNA/control probe or 23S rRNA/control probe and 16S rRNA/control probe ornfunctionally equivalent rRNA/control probe complexes; (e) assessing the integrity of said sample; and (f) evaluating microarray analysis results in view of said integrity assessment. n The present invention further relates to use of said methods as well as microarrays, devicesncomprising said microarrays, kits for carrying out said methods and computer products. |
| priorityDate | 2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 187.