http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1456654-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a82871cd2126b7cfd25f59e9ed692d8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2002-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05899ffec968eb2093e9b86e5f3ae9bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0d1588175148d09ab36e6411b16d8c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac1d9621d9558abb038b051b86b6ace1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da839e8e5243bec2ac403089b57967cb |
publicationDate | 2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1456654-A2 |
titleOfInvention | Use of elavl-1 gene in the detection and modulation of apoptosis |
abstract | The invention provides a method for detecting apoptosis in a cell comprising detecting a decrease in any one of: i) an ELAVL-1 (embryonic lethal, abnormal vision, Drosophila-like 1) polypeptide having an amino acid sequences as set out in SEQ ID NO:1; ii) a polypeptide having at least 80 % homology with i); iii) a nucleic acid encoding a polypeptide having the sequence set out in i) or ii); iv) a nucleic acid which hybridises under stringent conditions to the sequence set out in iii); or v) the complement of iii) or iv). The invention accordingly provides a method of modulating apoptosis by modulating ELAVL-1 gene expression and a method for identifying genes associated with ELAVL-1 gene expression and thus identifying other genes associated with apoptosis. The invention also provides a novel nucleic acid sequence encoding the promoter region for ELAVL-1. |
priorityDate | 2001-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1596.