http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1456348-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9eba6c40a33acd3726b5bfa7575ba6f2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-865 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-185 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 |
| filingDate | 2001-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b04a0943a7c7a05957f14e9bf9e58779 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4756119bc20b88b4f822f590beb3ce14 |
| publicationDate | 2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1456348-A1 |
| titleOfInvention | Saccharomyces-cerevisiae yeast strain with stable integration and expression of the nucleic acid sequence for a heterologous potassium ion channel |
| abstract | The invention relates to <i>Saccharomyces-cerevisiae</i> yeast strains with a stable integration and expression of the nucleic acid sequence for a heterologous potassium ion channel, in addition to a method for constructing said yeast strains. In particular, the invention relates to a <i>Saccharomyces-cerevisiae</i> yeast strain, in which all identified potassium ion translocation systems have been specifically deleted and to a <i>Saccharomyces-cerevisiae</i> yeast strain, into which in addition a nucleic acid sequence, which codes for a heterologous potassium ion channel, in particular for a mammalian potassium ion channel such as the human erg potassium ion channel (HERG), is integrated in a stable manner into the yeast genome and is expressed. The invention also relates to a method for the stable integration of heterologous potassium ion channel proteins into a <i>Saccharomyces-cerevisiae</i> yeast strain and to a method for detecting specific modulators of mammalian potassium ion channels, using said yeast strains. |
| priorityDate | 2001-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.