http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1453959-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44831c42834a8231673a6c2068249f64 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5085 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-553 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-55 |
| filingDate | 2002-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afe62ca9f89d4493106d51c55271553b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbfa000234556b5b72877970d55458e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa73660336819455267ebc40d3dbad76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fe46085517b201043da4399c4caf94f |
| publicationDate | 2004-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1453959-A2 |
| titleOfInvention | Method for the selection and identification of peptide or protein molecules by means of phase display |
| abstract | The invention relates to a method for the selection and identification of at least one representative (interaction partner) from a plurality of peptide or protein molecules, which can specifically interact with at least one representative from a plurality of target molecules, forming a bond. The inventive method comprises the following steps: (a) a virus system consisting of a plurality of viruses, wherein each virus respectively presents at least one representative from the plurality of peptide or protein molecules on the surface thereof, is brought into contact with the plurality of target molecules (ligands) which are immobilized on the surface of a solid phase carrier such that they are position addressable in a two-dimensional grid; (b) unbound viruses are removed from the surface thereof; and (c) the interaction partner is identified by detection and determination of the position of the bond between the immobilized ligand and the interaction partner presented by the virus with the aid of a marker-free detection method. The described method makes it possible to concentrate viruses presenting interaction partners by means of an optionally cyclic repetition of selection. Optionally, selected interaction partners are recombinantly expressed after identification of the coding nucleotide sequence. . |
| priorityDate | 2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 177.