| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dedc8e60e323a58ca2a7275d62d5b587 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 |
| filingDate |
2002-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0f2146d81e0846314f7bd6295393b4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dcb3d998215a6d8b46c82126462a491
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06048942bf3ce3170a23a21d293b58b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff3da1710639829578782848823ebe80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f6151e73d2e9d8aaad3d7a663113ce0 |
| publicationDate |
2004-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1448607-A1 |
| titleOfInvention |
Composition and method to homogeneously modify or cross-link chitosan under neutral conditions |
| abstract |
In accordance with the present invention there is provided a new composition and method for chemically modifying chitosan, including N-substituting or N-cross-linking, under homogeneous conditions by providing neutral aqueous chitosan solutions with enhanced reactivity. The method comprises the steps of i) preparing a clear aqueous solution of chitosan, said solution comprising 0.1 to 10% by weight of a chitosan, and 0.1 to 20% by weight of at least one buffering agent having a pKa between 6.0 and 7.6, said solution having a pH ranging from 6.8 to 7.2; and ii) dissolving homogeneously at least one reagent into the solution of step a), said reagent being reactive toward amine groups of chitosan; and said reagent being at a concentration from 0.01 to 10% by weight. The chitosan in the aqueous solution is chemically modified or cross-linked by a selective substitution on the amino group of chitosan |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828319-B2 |
| priorityDate |
2001-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |