abstract |
The present invention is directed to novel 1,2,4-thiadiazol-2-ium derivatives of the formula (I); wherein R?1, R2 and R4¿ are ring containing radicals, R3 is H, alkyl, alkenyl or alkynyl, useful as agonists or antagonists of the melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatement of metabolic, CNS and dermatological disorders. |