| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4717
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2002-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a47d716c6af6d67a9717e20b74adf56 |
| publicationDate |
2004-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1443111-A1 |
| titleOfInvention |
Desmin gene having novel point mutation causative of dilated cardiomyopathy |
| abstract |
The present invention is intended to elucidate the cause of severencardiomyopathy in subline (T) not manifesting the macroscopic cardiac hypertrophy,nwhich has been separated from a hamster (B) with hypertrophic cardiomyopathy andnclarify the pathogenic cause of dilated cardiomyopathy, thereby establishing a methodnof detecting and identifying dilated cardiomyopathy and a method of preventing andntreating the same. The present invention relates to a desmin gene having a pointnmutation at the site corresponding to the 571-position of the base sequence in thencDNA translation region of Syrian hamster; a polypeptide thereof; and annoligonucleotide consisting of 5 to 250 bases including the point mutation site or annoligonucleotide having a sequence complementary thereto. Moreover, the presentninvention relates to a method of detecting and identifying the point mutation at the sitencorresponding to the 571-position of the base sequence in the cDNA translation regionnof Syrian hamster to judge whether or not it is a gene causative of hereditaryncardiomyopathy. |
| priorityDate |
2001-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |