| abstract |
The invention provides isolated nucleic acids molecules, designated 69583 and 85924 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 69583 or 85924 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 69583 or 85924 gene has been introduced or disrupted. The invention still further provides isolated 69583 or 85924 proteins, fusion proteins, antigenic peptides and anti-69583 or -85924 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |