| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80787665b837ed3eb503bbcd27c0043a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F31-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F33-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-1097
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M47-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F13-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-08 |
| filingDate |
2004-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae5b06db64c05f1de4cb09b5f16897e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_762048570d53887839480ea233f32f31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24bde668b2bf83eb19a383345e91b6d7 |
| publicationDate |
2004-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1437597-A1 |
| titleOfInvention |
Protein measurement method in protein production plant by cell culture and apparatus thereof |
| abstract |
The invention relates to a method and an apparatusnfor automatic quantitative protein measurementnwithout risks of bacterial or microbiological contaminationnin each process step. The apparatus comprises ansampling unit (14) for automatically collecting a samplenliquid online from at least one operation process of ancell culture step (wherein an antibody or other proteinsnare produced and secreted into the culture medium), anseparation step or a culture product purification stepnin a plant for culturing biological cells to produce anprotein, a preprocessing unit (15) for performing dilutionnand/or filtration of the sample liquid to adjustnthe liquid composition, a reaction unit (9) having ancross-sectional area of 0.04 mm 2 or less for quantitativelynmeasuring a protein contained in the adjustednliquid using an antigen-antibody reaction, a measurementnunit (16) for quantitatively measuring the protein accordingnto the result of the reaction, a control unitn(17) for automatically controlling operations of thenabove units constituting the apparatus, and recordingnunit (18) for recording the measurement results. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112295622-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101726486-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2615635-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111617812-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021254412-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975429-B2 |
| priorityDate |
2003-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |