http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1429789-B1

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filingDate 2002-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ee8237a41ff22d0b7eedbd2c60065bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a53b5931b45427f0f2cd45b4948de8e
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publicationDate 2008-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1429789-B1
titleOfInvention Anti-infectious carbohydrates
abstract Neutral, linear or branched oligosaccharides (I), having a structure based on galactose, glucose and N-acetylated galactosamine and/or glucosamine moieties, are used for reducing or inhibiting the invasion and infection of mammalian cells by pathogens and for combating diseases caused by the pathogens. The use of neutral, linear or branched oligosaccharides (I) is claimed for reducing or inhibiting the invasion and infection of mammalian cells by pathogens and for combating diseases caused by the pathogens, where (I) comprises: (a) a base unit of formula R-(Gal(R)-HexNAc)-Gal(R)-Glc; (b) 0-19 further units of formula R-(Gal(R)-HexNAc)-, directly or indirectly linked to the base units; and (c) a terminal (Gal-HexNAc)-unit. Gal : galactose unit Glc : glucose unit; HexNAc : N-acetylated galactosamine (GalNAc) or N-acetylated glucosamine (GlcNAc) unit; R : deoxyhexose residue, beta 1-3 or beta 1-6 glycosidically bonded to the HexNAc moiety of the adjacent (Gal-HexNAc) unit (b) or to the galactose moiety of a terminal (Gal-HexNAc) unit (c); or is absent; a terminal unit (c), to which at least one deoxyhexose unit R is bonded, may carry further deoxyhexose residues. Independent claims are also included for the following: (i) nutritional, dietetic or pharmaceutical compositions (other than human milk), containing (I), conventional additives (such as diluents, humectants, thickeners, flavorings, sweeteners and/or carriers) and optionally other active agents; and (ii) a corresponding treatment method, involving administration of (I) or compositions as in (i) to humans or animals. ACTIVITY : Antibacterial; Virucide. MECHANISM OF ACTION : Blocking or modifying cell surface receptors; inhibiting adhesions of pathogens to cell surfaces.
priorityDate 2001-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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