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publicationDate 2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1428874-A2
titleOfInvention Lipase variant
abstract Certain variants of Lipolase (wild-type Humicola lanuginosa lipase) have anparticularly good first-wash performance in a detergent solution. The variants shouldncomprise one or more substitutions with positive amino acids near the N-terminal innthe three-dimensional structure. The variants should further comprise a peptidenaddition at the C-terminal and/or should meet certain limitations on electricallyncharged amino acids at positions 90-101 and 210.
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