abstract |
A pharmaceutical unit dosage form comprising a therapeutically effective dose of a 4-phenylbutyric acid salt having prolonged release of the active ingredient, being suitable for alleviating and curing various diseases upon once or twice daily oral administration, a method of preparation of said pharmaceutical formulation and the use thereof for the treatment of benign prostate hyperplasy, cancer, leukemias, cystic fibrosis, AIDS, kidney and liver diseases, thalassemia and urea cycle disorders comprising the twice-daily oral administration of a therapeutically effective dosage thereof to a patient. |