http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1426376-A4
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f4c2477bdea308bc9dec3feded37457 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-20 |
| filingDate | 2002-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da6d2b930c28ec942750638a5a5fd7c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_253b88625297ceb3b768a8468ebe57b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ce1de1c0681cb116a17e9aef0440e55 |
| publicationDate | 2004-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1426376-A4 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF CARBAPENEM-BASED ANTIBIOTICS |
| abstract | A process for the preparation of carbapenem antibiotics, which is freed from the two disadvantages: (1) use of column chromatography and (2) recovery of a difficultly soluble salt and by which the objective compounds can be efficiently prepared in a short period. Specifically, a process for the preparation of compounds represented by the general formula (IV), salts thereof, or hydrates of both, characterized by reacting a compound represented by the general formula (I) with a compound represented by the general formula (II): X - H (wherein X is a member selected from the group consisting of substituents represented by the formulae (X-1) to (X-8)) to thereby obtain a compound represented by the general formula (III) or a salt thereof, converting the compound (III) or salt thereof into a compound represented by the general formula (IV) or a salt thereof through the removal of the protective group (R3), and purifying the compounds (IV) or salt thereof by crystallization. (I) (X-1) (X-2) (X-3) (X-4) (X-5) (X-6) (X-7) (X-8) (III) (IV) |
| priorityDate | 2001-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.