abstract |
A medicinal composition comprising: (a) a compound represented by the following general formula (I): (I) (wherein R1 represents hydrogen or hydroxy) or an acid addition salt or hydrate of the compound; and (b) at least one member selected from the group of acceptable drugs consisting of a cerebral vasodilator, vasodilator agent, brain-protective agent, cerebral metabolism activator, anticoagulant agent, antithrombocytic agent, thrombolytic agent, alleviator for mental disorders, hypotensive drug, remedy for angina pectoris, diuretic agent, cardiac restorative, antiarrhythmic agent, hyperlipemia remedy, and immunosuppressant. It is useful as a preventive or remedy for cerebrovascular disorders and cardiopathy. |