| abstract |
Compositions and methods for preventing, treating and detecting leishmaniasisnand stimulating immune responses in patients are disclosed. The compoundsnprovided include polypeptides that contain at least an immunogenic portion ofnone or more Leishmania antigens, or a variant thereof. Vaccines andnpharmaceutical compositions comprising such polypeptides, or DNA moleculesnencoding such polypeptides, are also provided and may be used, for example,nfor the prevention and therapy of leishmaniasis, as well as for the detection ofn Leishmania infection. |