http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1422235-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e19ed5092514d4f22acfa3bc98b8b572 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
filingDate | 2002-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e15e923f29aa3f848b368c90c470971 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b931a051ec6c18d5823592cd6e0118f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09210d17e3591de3019e2e7af7052a14 |
publicationDate | 2004-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1422235-A1 |
titleOfInvention | Stereoselective method of producing 6alpha-fluoropregnanes and intermediaries |
abstract | 6α-fluorpregnanes (I), where the dotted line betweennpositions 1 and 2 represents a single or double bond; R1 isnOH, OCOR 2 , X, SO 3 R 3 , or an (R 7 )(R 8 )(R 9 )SiO- group, where X isnhalogen, R 2 and R 3 are C 1-6 alkyl or phenyl optionallynsubstituted by C 1-4 alkyl, and R 7 , R 8 and R 9 , equal orndifferent, are C 1-6 alkyl or phenyl optionallynsubstituted by C 1-4 alkyl, can be obtained by means of a highnstereoselectivity process comprising reacting a 3-(trisubstituted)silyloxy-pregna-3,5-dienen(IV) with anfluorinating agent selected among N-fluorosulfonimides and N-fluorosulfonamides.nThe 6α-fluorpregnanes (I) arenintermediates for the synthesis of steroids useful as anti-inflammatorynand anti-asthmatic agents. |
priorityDate | 2001-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.