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filingDate 2002-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ed12cb2b5c6fcbcb91bc5b53892926
publicationDate 2007-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1416958-B1
titleOfInvention Vaccine composition comprising at least two valences, one enhanced with adjuvant and not the other
abstract A vaccine composition comprising two valences is provided: (i) a first valence which is adjuvant-enhanced with aluminum hydroxide and (ii) a second valence which contains a polysaccharide of bacterial capsule comprising one or more o-acetyl groups and which is not adsorbed with aluminum oxide due to the presence of a protecting compound which may be a phosphate, a citrate or a carbonate and which prevents the adsorption. The first valence can be any vaccine valence. In one particular embodiment, the vaccine composition contains (i) Hepatitis A valence, adsorbed on aluminum hydroxide and (ii) the typhoid fever valence formed by the polysaccharide Vi of the Salmonella typhi capsule.
priorityDate 2001-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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