Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 |
filingDate |
2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62f05e244bee3a0e1d13654ba14c5c80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c88fa968cf0f31f1ffb917ab7f033f1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e9c9134206455fe60dbfd43de3d8959 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f618bd81574424f1bd99fd5694940ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67c86d97f2bcc88320dfa6e929deb1be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c142d1a930c9f8070ece853377016c5 |
publicationDate |
2004-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1416917-A1 |
titleOfInvention |
Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (mct) |
abstract |
A process for the preparation of a stable dispersion of solid particles, in an aqueous medium comprising combining (a) a first solution comprising a substantially water-insoluble substance, a water-miscible organic solvent and an inhibitor with (b) an aqueous phase comprising water and optionally a stabiliser, thereby precipitating solid particles comprising the inhibitor and the substantially water-insoluble substance; and optionally removing the water-miscible organic solvent; wherein the inhibitor is a non-polymeric hydrophobic organic compound as defined in the description. The process provides a dispersion of solid particles in an aqueous medium, which particles exhibit reduced or substantially no particle growth mediated by Ostwald ripening. |
priorityDate |
2001-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |